Synergistic anticancer effect
WebDec 16, 2024 · To confirm whether the synergistic anticancer effect of ZnPPIX and DHA exists in vivo, we lastly carried out animal studies using either drug or both to treat tumor … WebNov 5, 2024 · Functional experiments suggested that combined chidamide and etoposide treatment exerted synergistic antiproliferation effect and enhanced cell apoptotic death both in vitro and in vivo. Furthermore, the expression of DNA damage related proteins was detected and we also examined the alternations in histone acetylation, cell cycle …
Synergistic anticancer effect
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WebJan 12, 2024 · Bufalin (BFL) and cinobufagin (CBF) are the principal bioactive constituents of Chansu, a widely used traditional Chinese medicine (TCM). The synergistic effects of potential active components are responsible for the bioactivities of TCM. Our results showed that the cotreatment with BFL and CBF confers superior anticancer efficacy compared to … WebSep 30, 2024 · Strikingly, this synergistic effect was also closely related to the co-suppression of ERK and AKT signaling pathways. Furthermore, compound 3 significantly enhanced the suppression of SF on tumor growth in the HepG2 xenograft model, with a 79.3% inhibition ratio at high concentration, without systemic toxicity, compared to either …
WebOct 30, 2024 · A growing number of studies have focused on whether the combination of prescription medications and anticancer herbs could achieve a synergistic effect and reduce side effects [12, 13]. Crocetin, a sort of carotenoid, has reportedly exhibited biomedical properties, including anticancer properties as well as less or non-toxicity to … WebSynergistic Dose Permutation of Isolated Alkaloid and Sterol for Anticancer Effect on Young Swiss Albino Mice. Introduction: Synergy is defined as an interaction of some substances …
WebSep 8, 2024 · Last but not least, co-delivery of multiple drugs or combined treatment with the second drug confers a synergistic antitumor therapeutic effect (Ma et al., 2013). When it comes to the approaches to drug delivery in vivo, there are usually two ways that include passive and active targeting effects (Attia et al., 2024). WebIn ovarian cancer cell lines, overexpression of HDAC isoforms resulted in resistance to cisplatin, 21 and combination of cisplatin with panobinostat, a HDACI, enhanced ovarian cells sensitivity. 22 Synergistic anticancer effect was also evident when cisplatin was combined with belinostat in NSCLC cells. 22,23 In patients with NSCLC, HDAC class ...
WebCationic anticancer peptides, which can induce tumor cell immunogenic death and further promote systemic tumor-specific immune responses, have offered a promising solution …
WebIn this study, we tested the synergistic anticancer antiproliferative effects of combinations of PTX and 5-DMN on CL1-5 lung cancer cells through the MTT and propidium iodide … bramahafen germany cityWebThe results indicate that the combination of PTX and Andro exert significant synergistic anticancer effect on A549 cells in vitro and in vivo. The synergy may be the result of the … bramah weatherWebApr 1, 2024 · Glutathione-Triggered Mitochondria-Targeting Reassembly from Polymeric Micelles to Nanofibers for a Synergistic Anticancer Effect. Jingbo Wang. Jingbo Wang. … hagberg and donovan theoryWebJun 27, 2016 · Ru(II) -Pt(II) complexes are a class of bioactive molecules of interest as anticancer agents that combine a light-absorbing chromophore with a cisplatin-like unit. The results of a DFT and TDDFT investigation of a Ru(II) complex and its conjugate with a cis-PtCl2 moiety reveal that a synergistic eff … hagberg authorWebCationic anticancer peptides, which can induce tumor cell immunogenic death and further promote systemic tumor-specific immune responses, have offered a promising solution to relieve the tumor immunosuppressive microenvironment. However, peptide drugs are easily degraded and lack of targeting ability when administered systemically, leading to … bramah water closetWebApr 1, 2024 · Glutathione-Triggered Mitochondria-Targeting Reassembly from Polymeric Micelles to Nanofibers for a Synergistic Anticancer Effect. Jingbo Wang. Jingbo Wang. CAS Key Laboratory of Soft Matter Chemistry, Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei, Anhui 230026, China. bramah theoryWebJul 12, 2016 · For instance, a recent study has demonstrated the synergistic effect of the combination of metformin and aspirin in treating ... Yaacob, N. S., Kamal, N. N., and Norazmi, M. N. (2014). Synergistic anticancer effects of a bioactive subfraction of Strobilanthes crispus and tamoxifen on MCF-7 and MDA-MB-231 human breast cancer cell ... bramah road brixton